与“Ca“有关的文献报道

tes the SR of Ca 2+ and also results in a modest increase in [Ca 2+ ] because of the failure to return [Ca 2+ ] i to the

e in cytosolic Ca 2+, different Ca 2+ efflux routes were checked: Ca 2+ extrusion out of the cell and Ca 2+ uptake into

lar 45 Ca 2+ flux was then calculated using the formula J Ca 2+ = {(dpm)/( * [Ca 2+ ] tA )}10 6 ( 1 ), where J Ca 2+ is

intracellular Ca 2+ stores and blocking basolateral Ca 2+ entry suppresses the hypotonicity-induced [Ca 2+ ] i changes

Ca 2+ absorption and mRNA expression levels of genes encoding duodenal Ca 2+ transport proteins. A : changes in serum Ca

d Ca 2+ mobilization and [Ca 2+ ] i oscillations in IMCD. Buffering the changes of [Ca 2+ ] i with an intracellular Ca 2

on [Ca 2+ ] i. Removal of Ca 2+ from the extracellular medium had no significant effect on the peak increase in [Ca 2+

Ca 2+ -free medium to prevent Ca 2+ overload and exposed for a maximum of 5 min to a Krebs solution containing 1.5 mM Ca

ell proliferation is associated with enhanced capacitative Ca(2) entry in human arterial myocytes. Am J Physiol 1999, 27

moves Ca 2+ from the medium, or with nitrendipine, an L-type Ca 2+ channel antagonist, both markedly inhibited [Ca 2+ ]

ESULTS [Ca 2+ ] i Measurements in Afferent Arterioles [Ca 2+ ] i responses to ET-1. Afferent arterioles in Ca 2+ -cont

volves a decrease in [Ca 2+ ] i by inhibition of Ca 2+ entry. In VSM cells of rat tail artery, Ca 2+ entry through volt

lar Ca 2+ ). The sEH inhibitor did not affect Ca 2+ influx in CYP2C9-deficient cells but significantly increased Ca 2+

se in [Ca 2+ ] i. The flow-induced Ca 2+ response consists of an initial Ca 2+ influx via a stretch-activated Ca 2+ cha

+ /Ca 2+ 交换 Na 2+ /Ca 2+ 交换是将细胞内Ca 2+ 排出细胞外的另一种形式。Na 2+ /Ca 2+ 交换广泛存在于各种细胞，在可兴奋细胞如心肌细胞和神经细胞中对钙转运起主要作用 ［33］ 。Na + /Ca 2+

ds CA-125 ovary caner CEA CA-125是存在于卵巢癌细胞表面的一种糖蛋白，为上皮性卵巢癌腺腔上皮胚胎发育期所分泌的抗原决定簇，是随访卵巢癌患者一种有价值的检测指标。正常卵巢表面上皮不存在CA-125，发现CA-12

指标，也大大提高了工作效率和测定结果的重复性和准确性，已得到临床医生的普遍认可。我科自2001年购进1台Sysmex CA-530型全自动血液凝固仪，该仪器具有体积小、操作简便、性能稳定等优点。它能同时测定5种参数，最大处理能力大约50项/

wide range of Ca 2+ channels, including voltage-gated and epithelial Ca 2+ channels ( 4, 12 ). The net Ca 2+ uptake in

derlying Ca 2+ -activated Cl - channels have an absolute requirement for intracellular Ca 2+ to open. At a [Ca 2+ ] i o

皮癌患者的癌组织及血清中存在CA-125，说明CA-125是一种与卵巢癌相关的抗原 ［1，2］ 。从表1中结果可见，卵巢癌患者血清中CA-125水平呈高值趋势，阳性检出率为94.1%，而卵巢良性肿瘤患者血清中CA-125水平呈低浓度升高，阳

ted IP 3 -mediated Ca 2+ release from the ER and ER Ca 2+ store depletion. Subsequent addition of Ca 2+ (2 mM) in the m

expressed Ca 2+ -ATPase PMCA2, have a very low endolymphatic Ca 2+ concentration ( 45 ). Reabsorption of Ca 2+ may ent

uorescent signal to [Ca 2+ ] i was performed by calibration with ionomycin (30 µM; maximum Ca 2+ concentration) fo

iculum Ca 2+ -ATPase. Treatment of cells with CPA causes a gradual increase in [Ca 2+ ] i due to a decrease in Ca 2+ reu

/4.2 by the CaR. The presence of high (5.0 mM) Ca o 2+ or low (0.5 mM) Ca o 2+ did not alter the efficiency of immunopre

ta Cruz, CA), unless otherwise reported. BAPTA/AM and Gö6976 were purchased from Calbiochem (La Jolla, CA). Anima

或CA 125 升高。（3）CA 125 半衰期（t 1/2 ）=t/2log（CA 1 /CA 2 ），其中CA 1 代表术后2周第1次化疗开始时CA 125 值，CA 2 代表化疗中首次正常CA 125 值或若干化疗开始后3个月内CA

位症Ⅱ、Ⅲ期患者血清CA 125 浓度升高，免疫组化亦显示子宫内异灶表面有CA 125 存在。在正常情况下，腹膜屏障只允许少量CA 125 抗原自腹膜进入血循环，而子宫内膜异位症患者由于内异灶种植部位腹膜被损伤，导致CA 125 抗原进入血

血清CA-125含量下降，一段时间后血清CA-125又升高，则表明有复发和转移。术前血清CA-125仅轻微增高而术后血清CA-125值又下降为正常者，患者往往仅限于原发灶未发生转移，病理细胞分化较好。因此，通过术前术后动态监测血清CA-1

（RI）明显下降，CA-125的水平则明显升高（除外肌层浸润深度）。结论 术前行彩超检测肿瘤内血流RI值及测定血清CA-125值对完善临床诊断，制定治疗方案有一定的意义。 关键词 子宫内膜癌 彩超血流RI值 CA-125

粒后出现腹胀，胃部不适感，减量后症状消失。 3 讨论 CA是由HPV所致的一种性传播疾病，复发率较高，目前临床没有有效的防止其复发的特效药及治疗手段。当前，不少学者认为CA的复发与亚临床感染有关。亚临床感染可通过派特灵药盒中的鉴别液

因此，笔者认为血清CA19-9和CA-125联合检测不但对妇科恶性肿瘤也有显著的敏感性。因此，CA19-9和CA-125联合检测在临床妇科肿瘤的良恶性诊断中具有一定的指导意义，但不能绝对化，不能简单地认为CA-125、CA19-9升高就是恶

验结果的影响不是很大，加入Ca（OH）2饱和溶液的方法是可取的。用此方法我们检测了30多个批号的采血袋，均与生产厂家用家兔法检测的结果一致，说明该方法可以作为血液中心或血站对采血袋进行质量监控的方法。 Ca（OH）2的理化性质比较稳

细胞内Ca(2+)储存远大于HEK-293所储存的Ca(2+)。对HeLa细胞内Ca(2+)进行检测时发现，TrkPC1的表达可增强由组胺激发的胞浆内Ca(2+)的增加，甚至即使在细胞外Ca(2+)不存在的情况下也同样可增加胞浆内Ca(2+

示丙泊酚对Ca 2+ -ATPase活性的影响呈双相，在低浓度（≤20μmol/L）使酶的活性升高，高浓度的丙泊酚（≥50μmol/L）对酶具有抑制作用，且随浓度的升高Ca 2+-ATPase活性逐渐下降，而低浓度硫喷妥钠对Ca 2+ -

比较,2和4μg/ml利多卡因对L-型Ca^2＋单通道的功能无明显影响,8和16μg/ml利多卡因使L-型Ca^2＋单通道开放时间延长,开放概率增加（P〈0.05）;32μg/ml利多卡因使L-型Ca^2＋单通道开放时间缩短,开放概率降低